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No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells
Inactivation of mammalian telomerase leads to telomere attrition, eventually culminating in uncapped telomeres, which elicit a DNA damage response and cell cycle arrest or death. In some instances, telomerase modulation evokes a response not obviously attributable to changes in telomere length. One...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663532/ https://ncbi.nlm.nih.gov/pubmed/19071232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.11.009 |
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