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Measuring Cancer Hallmark Mediation of the TET1 Glioma Survival Effect with Linked Neural-Network Based Mediation Experiments

This paper examines the effect of TET1 expression on survival in glioma patients using open-access data from the Genomic Data Commons. A neural network-based survival model was built on expression data from a selection of genes most affected by TET1 knockdown with a median cross-validated survival c...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Luechtefeld, Thomas, Lin, Nole, Paller, Channing, Kuhns, Katherine, Laterra, John J., Bressler, Joseph P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264360/
https://ncbi.nlm.nih.gov/pubmed/32483272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65369-3
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