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Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes

Given the skyrocketing costs to develop new drugs, repositioning of approved drugs, such as histone deacetylase (HDAC) inhibitors, may be a promising strategy to develop novel therapies. However, a gap exists in the understanding and advancement of these agents to meaningful translation for which ne...

詳細記述

保存先:
書誌詳細
出版年:Epigenetics
主要な著者: Rafehi, Haloom, Kaspi, Antony, Ziemann, Mark, Okabe, Jun, Karagiannis, Tom C., El-Osta, Assam
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788408/
https://ncbi.nlm.nih.gov/pubmed/28886276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1371892
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