HDAC Inhibition in Vascular Endothelial Cells Regulates the Expression of ncRNAs

While clinical and pre-clinical trials indicate efficacy of histone deacetylase (HDAC) inhibitors in disease mediated by dynamic lysine modification, the impact on the expression of non-coding RNAs (ncRNAs) remains poorly understood. In this study, we investigate high throughput RNA sequencing data...

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Detalhes bibliográficos
Main Authors: Haloom Rafehi, Assam El-Osta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-05-01
Colecção:Non-Coding RNA
Assuntos:
non-coding RNA
epigenetics
HDAC inhibitors
histone acetylation
histone methylation
endothelial cells
vascular
Acesso em linha:http://www.mdpi.com/2311-553X/2/2/4
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