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Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells

Recurrent mutations at key lysine residues in the histone variant H3.3 are thought to play an etiologic role in the development of distinct subsets of pediatric gliomas and bone and cartilage cancers. H3.3K36M is one such mutation that was originally identified in chondroblastomas, and its expressio...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Sankaran, Saumya M., Gozani, Or
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788406/
https://ncbi.nlm.nih.gov/pubmed/28933651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1377870
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