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Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development, are complex and incompletely understood. We have developed a model to...
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| Publicado no: | Mol Syst Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787708/ https://ncbi.nlm.nih.gov/pubmed/29378814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177952 |
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