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Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development, are complex and incompletely understood. We have developed a model to...
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| Publicat a: | Mol Syst Biol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787708/ https://ncbi.nlm.nih.gov/pubmed/29378814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177952 |
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