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Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development, are complex and incompletely understood. We have developed a model to...
Shranjeno v:
| izdano v: | Mol Syst Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787708/ https://ncbi.nlm.nih.gov/pubmed/29378814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177952 |
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