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Pregestational type 2 diabetes mellitus induces cardiac hypertrophy in the murine embryo through cardiac remodeling and fibrosis

BACKGROUND: Cardiac hypertrophy is highly prevalent in patients with type 2 diabetes mellitus (T2DM). Experimental evidence has implied that pregnant women with T2DM and their children are at an increased risk of cardiovascular diseases. Our previous mouse model study has revealed that maternal T2DM...

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Detalhes bibliográficos
Publicado no:Am J Obstet Gynecol
Main Authors: Lin, Xue, Yang, Penghua, Reece, E. Albert, Yang, Peixin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787338/
https://ncbi.nlm.nih.gov/pubmed/28412087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2017.04.008
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