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Pregestational type 2 diabetes mellitus induces cardiac hypertrophy in the murine embryo through cardiac remodeling and fibrosis

BACKGROUND: Cardiac hypertrophy is highly prevalent in patients with type 2 diabetes mellitus (T2DM). Experimental evidence has implied that pregnant women with T2DM and their children are at an increased risk of cardiovascular diseases. Our previous mouse model study has revealed that maternal T2DM...

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Bibliografische gegevens
Gepubliceerd in:Am J Obstet Gynecol
Hoofdauteurs: Lin, Xue, Yang, Penghua, Reece, E. Albert, Yang, Peixin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787338/
https://ncbi.nlm.nih.gov/pubmed/28412087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2017.04.008
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