Revisiting Activation of and Mechanism of Resistance to Compound IQG-607 in Mycobacterium tuberculosis

IQG-607 is a metal complex previously reported as a promising anti-tuberculosis (TB) drug against isoniazid (INH)-resistant strains of Mycobacterium tuberculosis. Unexpectedly, we found that INH-resistant clinical isolates were resistant to IQG-607. Spontaneous mutants resistant to IQG-607 were subj...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Abbadi, Bruno L., Villela, Anne D., Rodrigues-Junior, Valnês S., Subtil, Fernanda T., Dalberto, Pedro F., Pinheiro, Ana P. S., Santos, Diógenes S., Machado, Pablo, Basso, Luiz A., Bizarro, Cristiano V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786794/
https://ncbi.nlm.nih.gov/pubmed/29158273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02222-17
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker