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Substrate Specificity for Bacterial RNases HII and HIII Is Influenced by Metal Availability

We tested the activities of four predicated RNase H enzymes, including two RNase HI-type enzymes, in addition to RNase HII (RnhB) and RNase HIII (RnhC), on several RNA-DNA hybrid substrates with different divalent metal cations. We found that the two RNase HI-type enzymes, YpdQ and YpeP, failed to s...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Randall, Justin R., Hirst, William G., Simmons, Lyle A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786700/
https://ncbi.nlm.nih.gov/pubmed/29084857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00401-17
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