The Deletion of rnhB in Mycobacterium smegmatis Does Not Affect the Level of RNase HII Substrates or Influence Genome Stability

RNase HII removes RNA from RNA/DNA hybrids, such as single ribonucleotides and RNA primers generated during DNA synthesis. Both, RNase HII substrates and RNase HII deficiency have been associated with genome instability in several organisms, and genome instability is a major force leading to the acq...

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Bibliographic Details
Published in:PLoS One
Main Authors: Minias, Alina E., Brzostek, Anna M., Minias, Piotr, Dziadek, Jaroslaw
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300193/
https://ncbi.nlm.nih.gov/pubmed/25603150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115521
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