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An inter-domain regulatory mechanism controls toxic activities of PrP(C)

The normal function of PrP(C), the cellular prion protein, has remained mysterious since its first description over 30 years ago. Amazingly, although complete deletion of the gene encoding PrP(C) has little phenotypic consequence, expression in transgenic mice of PrP molecules carrying certain inter...

詳細記述

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書誌詳細
出版年:Prion
主要な著者: McDonald, Alex J., Wu, Bei, Harris, David A.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786360/
https://ncbi.nlm.nih.gov/pubmed/28960140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1384894
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