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An inter-domain regulatory mechanism controls toxic activities of PrP(C)

The normal function of PrP(C), the cellular prion protein, has remained mysterious since its first description over 30 years ago. Amazingly, although complete deletion of the gene encoding PrP(C) has little phenotypic consequence, expression in transgenic mice of PrP molecules carrying certain inter...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: McDonald, Alex J., Wu, Bei, Harris, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786360/
https://ncbi.nlm.nih.gov/pubmed/28960140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1384894
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