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The P’s and Q’s of cellular PrP-Aβ interactions
Prion disease research has opened up the “black-box” of neurodegeneration, defining a key role for protein misfolding wherein a predominantly alpha-helical precursor protein, PrP(C), is converted to a disease-associated, β-sheet enriched isoform called PrP(Sc). In Alzheimer disease (AD) the Aβ pepti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609064/ https://ncbi.nlm.nih.gov/pubmed/22874673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.20675 |
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