Ca(2+)-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels

In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow I(KS) potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias. The proximal Kv7.1 C-terminus binds calmodulin (CaM) and phosphatidylinositol-4,5-bisphospha...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Channels (Austin)
Main Authors: Tobelaim, William S., Dvir, Meidan, Lebel, Guy, Cui, Meng, Buki, Tal, Peretz, Asher, Marom, Milit, Haitin, Yoni, Logothetis, Diomedes E., Hirsch, Joel A., Attali, Bernard
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Article Addendum
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786183/
https://ncbi.nlm.nih.gov/pubmed/28976808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1388478
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares