Ca(2+)-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels

In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow I(KS) potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias. The proximal Kv7.1 C-terminus binds calmodulin (CaM) and phosphatidylinositol-4,5-bisphospha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Channels (Austin)
Prif Awduron: Tobelaim, William S., Dvir, Meidan, Lebel, Guy, Cui, Meng, Buki, Tal, Peretz, Asher, Marom, Milit, Haitin, Yoni, Logothetis, Diomedes E., Hirsch, Joel A., Attali, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Article Addendum
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786183/
https://ncbi.nlm.nih.gov/pubmed/28976808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1388478
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