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Ca(2+)-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels
In the heart, co-assembly of Kv7.1 with KCNE1 produces the slow I(KS) potassium current, which repolarizes the cardiac action potential and mutations in human Kv7.1 and KCNE1 genes cause cardiac arrhythmias. The proximal Kv7.1 C-terminus binds calmodulin (CaM) and phosphatidylinositol-4,5-bisphospha...
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| Publicado no: | Channels (Austin) |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5786183/ https://ncbi.nlm.nih.gov/pubmed/28976808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1388478 |
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