טוען...

Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC–ESI–MS/MS: An application for pharmacokinetic studies

Hydroxychloroquine (HCQ) has been shown to disrupt autophagy and sensitize cancer cells to radiation and chemotherapeutic agents. However, the optimal delivery method, dose, and tumor concentrations required for these effects are not known. This is in part due to a lack of sensitive and reproducible...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Chromatogr B Analyt Technol Biomed Life Sci
Main Authors: Chhonker, Yashpal S., Sleightholm, Richard L, Li, Jing, Oupický, David, Murry, Daryl J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786170/
https://ncbi.nlm.nih.gov/pubmed/29207305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2017.11.026
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