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LC–MS/MS method for simultaneous determination of diethylcarbamazine, albendazole and albendazole metabolites in human plasma: Application to a clinical pharmacokinetic study

Combination therapy with anti-filarial drugs is now widely used for treatment of lymphatic filariasis. A rapid, selective, and sensitive liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) method was developed and validated for simultaneous quantitation of diethylcarbamazine (DEC)...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Chhonker, Yashpal S., Edi, Constant, Murry, Daryl J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814678/
https://ncbi.nlm.nih.gov/pubmed/29310051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2017.12.037
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