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Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo
The present study was designed to investigate if elevated copper level can be targeted to enhance the efficacy of a significant anticancer drug, imatinib (ITB). The antineoplastic activity of this drug was assessed in the HepG2, HEK-293, MCF-7 and MDA-MD-231 cells targeting elevated copper level as...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5786010/ https://ncbi.nlm.nih.gov/pubmed/29374195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19410-1 |
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