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Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo

The present study was designed to investigate if elevated copper level can be targeted to enhance the efficacy of a significant anticancer drug, imatinib (ITB). The antineoplastic activity of this drug was assessed in the HepG2, HEK-293, MCF-7 and MDA-MD-231 cells targeting elevated copper level as...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Hassan, Iftekhar, Khan, Azmat Ali, Aman, Shazia, Qamar, Wajhul, Ebaid, Hossam, Al-Tamimi, Jameel, Alhazza, Ibrahim M., Rady, Ahmed M.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786010/
https://ncbi.nlm.nih.gov/pubmed/29374195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19410-1
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