Cold adaptation of tRNA nucleotidyltransferases: A tradeoff in activity, stability and fidelity

Cold adaptation is an evolutionary process that has dramatic impact on enzymatic activity. Increased flexibility of the protein structure represents the main evolutionary strategy for efficient catalysis and reaction rates in the cold, but is achieved at the expense of structural stability. This res...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:RNA Biol
Asıl Yazarlar: Ernst, Felix G. M., Erber, Lieselotte, Sammler, Joana, Jühling, Frank, Betat, Heike, Mörl, Mario
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2017
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785979/
https://ncbi.nlm.nih.gov/pubmed/29099323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1391445
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