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Domain movements during CCA-addition: A new function for motif C in the catalytic core of the human tRNA nucleotidyltransferases

CCA-adding enzymes are highly specific RNA polymerases that synthesize and maintain the sequence CCA at the tRNA 3′-end. This nucleotide triplet is a prerequisite for tRNAs to be aminoacylated and to participate in protein biosynthesis. During CCA-addition, a set of highly conserved motifs in the ca...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Ernst, Felix G M, Rickert, Christian, Bluschke, Alexander, Betat, Heike, Steinhoff, Heinz-Jürgen, Mörl, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615804/
https://ncbi.nlm.nih.gov/pubmed/25849199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1018502
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