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Unusual evolution of a catalytic core element in CCA-adding enzymes
CCA-adding enzymes are polymerases existing in two distinct enzyme classes that both synthesize the C-C-A triplet at tRNA 3′-ends. Class II enzymes (found in bacteria and eukaryotes) carry a flexible loop in their catalytic core required for switching the specificity of the nucleotide binding pocket...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910056/ https://ncbi.nlm.nih.gov/pubmed/20348137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq176 |
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