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Cold adaptation of tRNA nucleotidyltransferases: A tradeoff in activity, stability and fidelity

Cold adaptation is an evolutionary process that has dramatic impact on enzymatic activity. Increased flexibility of the protein structure represents the main evolutionary strategy for efficient catalysis and reaction rates in the cold, but is achieved at the expense of structural stability. This res...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Ernst, Felix G. M., Erber, Lieselotte, Sammler, Joana, Jühling, Frank, Betat, Heike, Mörl, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785979/
https://ncbi.nlm.nih.gov/pubmed/29099323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1391445
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