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The combined activation of K(Ca)3.1 and inhibition of K(v)11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells

BACKGROUND: Platinum-based drugs such as Cisplatin are commonly employed for cancer treatment. Despite an initial therapeutic response, Cisplatin treatment often results in the development of chemoresistance. To identify novel approaches to overcome Cisplatin resistance, we tested Cisplatin in combi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Br J Cancer
Main Authors: Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, K George, Becchetti, Andrea, Arcangeli, Annarosa
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785745/
https://ncbi.nlm.nih.gov/pubmed/29161243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.392
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