Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

Alzheimer's disease (AD) induces memory and cognitive impairment in the absence of motor and sensory deficits during its early and middle course. A major unresolved question is the basis for this selective neuronal vulnerability. Aβ, which plays a central role in AD pathogenesis, is generated t...

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Udgivet i:Stem Cell Reports
Main Authors: Muratore, Christina R., Zhou, Constance, Liao, Meichen, Fernandez, Marty A., Taylor, Walter M., Lagomarsino, Valentina N., Pearse, Richard V., Rice, Heather C., Negri, Joseph M., He, Amy, Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Zhou, Monica, Bennett, David A., Noggle, Scott, Love, J. Christopher, Selkoe, Dennis J., Young-Pearse, Tracy L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785690/
https://ncbi.nlm.nih.gov/pubmed/29153990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.10.015
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