Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

Alzheimer's disease (AD) induces memory and cognitive impairment in the absence of motor and sensory deficits during its early and middle course. A major unresolved question is the basis for this selective neuronal vulnerability. Aβ, which plays a central role in AD pathogenesis, is generated t...

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Publicado no:Stem Cell Reports
Main Authors: Muratore, Christina R., Zhou, Constance, Liao, Meichen, Fernandez, Marty A., Taylor, Walter M., Lagomarsino, Valentina N., Pearse, Richard V., Rice, Heather C., Negri, Joseph M., He, Amy, Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Zhou, Monica, Bennett, David A., Noggle, Scott, Love, J. Christopher, Selkoe, Dennis J., Young-Pearse, Tracy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785690/
https://ncbi.nlm.nih.gov/pubmed/29153990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.10.015
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