Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

Alzheimer's disease (AD) induces memory and cognitive impairment in the absence of motor and sensory deficits during its early and middle course. A major unresolved question is the basis for this selective neuronal vulnerability. Aβ, which plays a central role in AD pathogenesis, is generated t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Reports
Prif Awduron: Muratore, Christina R., Zhou, Constance, Liao, Meichen, Fernandez, Marty A., Taylor, Walter M., Lagomarsino, Valentina N., Pearse, Richard V., Rice, Heather C., Negri, Joseph M., He, Amy, Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Zhou, Monica, Bennett, David A., Noggle, Scott, Love, J. Christopher, Selkoe, Dennis J., Young-Pearse, Tracy L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785690/
https://ncbi.nlm.nih.gov/pubmed/29153990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.10.015
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