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RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance

RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation. In murine small intestinal epithelium, inducible RHOA deletion causes a loss of epithelial polarity, with disrupt...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Liu, Ming, Zhang, Zheng, Sampson, Leesa, Zhou, Xuan, Nalapareddy, Kodandaramireddy, Feng, Yuxin, Akunuru, Shailaja, Melendez, Jaime, Davis, Ashley Kuenzi, Bi, Feng, Geiger, Hartmut, Xin, Mei, Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785633/
https://ncbi.nlm.nih.gov/pubmed/29129684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.10.004
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