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Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts

Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such conflicts. However, little is known regarding how cells cope with sudden increases of transcription while replicating. Here, we report the exi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Duch, Alba, Canal, Berta, Barroso, Sonia I., García-Rubio, María, Seisenbacher, Gerhard, Aguilera, Andrés, de Nadal, Eulàlia, Posas, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785523/
https://ncbi.nlm.nih.gov/pubmed/29371596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02756-x
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