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The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription–replication conflicts

FACT (facilitates chromatin transcription) is a chromatin-reorganizing complex that swaps nucleosomes around the RNA polymerase during transcription elongation and has a role in replication that is not fully understood yet. Here we show that recombination factors are required for the survival of yea...

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Detalhes bibliográficos
Main Authors: Herrera-Moyano, Emilia, Mergui, Xénia, García-Rubio, María L., Barroso, Sonia, Aguilera, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015491/
https://ncbi.nlm.nih.gov/pubmed/24636987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.234070.113
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