Dinaciclib induces immunogenic cell death and enhances anti-PD1–mediated tumor suppression

Blockade of the checkpoint inhibitor programmed death 1 (PD1) has demonstrated remarkable success in the clinic for the treatment of cancer; however, a majority of tumors are resistant to anti-PD1 monotherapy. Numerous ongoing clinical combination therapy studies will likely reveal additional therap...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hossain, Dewan Md Sakib, Javaid, Sarah, Cai, Mingmei, Zhang, Chunsheng, Sawant, Anandi, Hinton, Marlene, Sathe, Manjiri, Grein, Jeff, Blumenschein, Wendy, Pinheiro, Elaine M., Chackerian, Alissa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785250/
https://ncbi.nlm.nih.gov/pubmed/29337311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94586
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