Oncolytic vaccines increase the response to PD-L1 blockade in immunogenic and poorly immunogenic tumors

Activation of immune checkpoint pathways and limited T- cell infiltration result in immunological escape of tumors. Although immune checkpoint inhibitors are currently approved for several types of cancers, the response rate is often limited by the lack of tumor specific T-cells within the malignant...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Feola, S., Capasso, C., Fusciello, M., Martins, B., Tähtinen, S., Medeot, M., Carpi, S., Frascaro, F., Ylosmäki, E., Peltonen, K., Pastore, L., Cerullo, V.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136871/
https://ncbi.nlm.nih.gov/pubmed/30221051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1457596
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