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Cell cycle regulation and anticancer drug discovery

Cellular growth, development, and differentiation are tightly controlled by a conserved biological mechanism: the cell cycle. This cycle is primarily regulated by cyclin-dependent kinase (CDK)-cyclin complexes, checkpoint kinases, and CDK inhibitors. Deregulation of the cell cycle is a hallmark of t...

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Pubblicato in:Cancer Biol Med
Autori principali: Bai, Jingwen, Li, Yaochen, Zhang, Guojun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Chinese Anti-Cancer Association 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785171/
https://ncbi.nlm.nih.gov/pubmed/29372101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2017.0033
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