Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

BACKGROUND: The metabolic basis of Alzheimer disease (AD) is poorly understood, and the relationships between systemic abnormalities in metabolism and AD pathogenesis are unclear. Understanding how global perturbations in metabolism are related to severity of AD neuropathology and the eventual expre...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Med
Prif Awduron: Varma, Vijay R., Oommen, Anup M., Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M., O’Brien, Richard, Pletnikova, Olga, Troncoso, Juan C., Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P. Murali, Saykin, Andrew J., Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784884/
https://ncbi.nlm.nih.gov/pubmed/29370177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002482
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