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A singular role of I(K1) promoting the development of cardiac automaticity during cardiomyocyte differentiation by I(K1)–induced activation of pacemaker current
The inward rectifier potassium current (I(K1)) is generally thought to suppress cardiac automaticity by hyperpolarizing membrane potential (MP). We recently observed that I(K1) could promote the spontaneously-firing automaticity induced by upregulation of pacemaker funny current (I(f)) in adult vent...
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| Pubblicato in: | Stem Cell Rev |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784831/ https://ncbi.nlm.nih.gov/pubmed/28623610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9745-1 |
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