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A singular role of I(K1) promoting the development of cardiac automaticity during cardiomyocyte differentiation by I(K1)–induced activation of pacemaker current

The inward rectifier potassium current (I(K1)) is generally thought to suppress cardiac automaticity by hyperpolarizing membrane potential (MP). We recently observed that I(K1) could promote the spontaneously-firing automaticity induced by upregulation of pacemaker funny current (I(f)) in adult vent...

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Detalles Bibliográficos
Publicado en:Stem Cell Rev
Main Authors: Sun, Yu, Timofeyev, Valeriy, Dennis, Adrienne, Bektik, Emre, Wan, Xiaoping, Laurita, Kenneth R., Deschênes, Isabelle, Li, Ronald A., Fu, Ji-Dong
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784831/
https://ncbi.nlm.nih.gov/pubmed/28623610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9745-1
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