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Synergistic effects of Inward Rectifier (I(K1)) and Pacemaker (I(f)) Currents on the Induction of Bioengineered Cardiac Automaticity
INTRODUCTION: Normal heart rhythms originate in the sinoatrial node. HCN-encoded funny current (I(f)) and the Kir2-encoded inward rectifier (I(K1)) counteract each other by respectively oscillating and stabilizing the negative resting membrane potential, controlling action potential firing. Therefor...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739246/ https://ncbi.nlm.nih.gov/pubmed/19460073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2009.01475.x |
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