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CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF‐κB activation and IL‐1β/IL‐6 secretion

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability. Anti‐inflammatory drugs and disease‐modifying anti‐rheumatic drugs (DMARDs) may improve RA process. However, in most patient...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Hong, Honghai, Zeng, Yingmin, Jian, Wenxuan, Li, Lei, Lin, Liying, Mo, Yousheng, Liu, Meiling, Fang, Shuhuan, Xia, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783872/
https://ncbi.nlm.nih.gov/pubmed/29083085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13414
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