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Inflammation-dependent secretion and splicing of IL-32γ in rheumatoid arthritis
Different splice variants of the proinflammatory cytokine IL-32 are found in various tissues; their putative differences in biological function remain unknown. In the present study, we report that IL-32γ is the most active isoform of the cytokine. Splicing to one less active IL-32β appears to be a s...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064318/ https://ncbi.nlm.nih.gov/pubmed/21383200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016005108 |
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