Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

BRAF V600E mutations occur frequently in malignant melanoma, but are rare in most malignant glioma subtypes. Besides, more benign brain tumors such as ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50–78%) and e...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Burger, Michael C., Ronellenfitsch, Michael W., Lorenz, Nadja I., Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim P., Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick N., Bähr, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783574/
https://ncbi.nlm.nih.gov/pubmed/29039591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.6013
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