Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

BRAF V600E mutations occur frequently in malignant melanoma, but are rare in most malignant glioma subtypes. Besides, more benign brain tumors such as ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50–78%) and e...

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Bibliografske podrobnosti
izdano v:Oncol Rep
Main Authors: Burger, Michael C., Ronellenfitsch, Michael W., Lorenz, Nadja I., Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim P., Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick N., Bähr, Oliver
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783574/
https://ncbi.nlm.nih.gov/pubmed/29039591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.6013
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