Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

BRAF V600E mutations occur frequently in malignant melanoma, but are rare in most malignant glioma subtypes. Besides, more benign brain tumors such as ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50–78%) and e...

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Publicado en:Oncol Rep
Autores principales: Burger, Michael C., Ronellenfitsch, Michael W., Lorenz, Nadja I., Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim P., Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick N., Bähr, Oliver
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2017
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783574/
https://ncbi.nlm.nih.gov/pubmed/29039591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.6013
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