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Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching
INTRODUCTION: Current treatment with vasodilators for pulmonary hypertension associated with respiratory diseases is limited by their inhibitory effect on hypoxic pulmonary vasoconstriction (HPV) and uncoupling effects on ventilation-perfusion (V’/Q’). Hypoxia is also a well-known modulator of the n...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5783366/ https://ncbi.nlm.nih.gov/pubmed/29364918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191239 |
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