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miR‐1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries
KEY POINTS: The expression of miR‐1 is increased in lungs from the Hyp/Su5416 PAH rat model. Pulmonary artery smooth muscle cells from this animal model are more depolarized and show decreased expression and activity of voltage‐dependent potassium channel (Kv)1.5. miR‐1 directly targets Kv1.5 channe...
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| Publicat a: | J Physiol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6375863/ https://ncbi.nlm.nih.gov/pubmed/29717493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276054 |
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