Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Elevated expression of the Zinc finger E-box binding homeobox transcription factor-2 (ZEB2) is correlated with poor prognosis and patient outcome in a variety of human cancer subtypes. Using a conditional gain-of-function mouse model, we recently demonstrated that ZEB2 is an oncogenic driver of imma...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Goossens, Steven, Peirs, Sofie, Van Loocke, Wouter, Wang, Jueqiong, Takawy, Mina, Matthijssens, Filip, Sonderegger, Stefan E., Haigh, Katharina, Nguyen, Thao, Vandamme, Niels, Costa, Magdaline, Carmichael, Catherine, Van Nieuwerburgh, Filip, Deforce, Dieter, Kleifeld, Oded, Curtis, David J., Berx, Geert, Van Vlierberghe, Pieter, Haigh, Jody J.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783288/
https://ncbi.nlm.nih.gov/pubmed/28069602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-721191
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料