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P06.20 EGFRvIII: a predictive marker for Temozolomide response in O6-methylguanine-DNA methyltransferase negative glioblastoma cells and tumor xenografts

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults with an estimated 5-year survival of less 10%. The current standard of care involves maximal tumor resection followed by radiation and chemotherapy with the alkylating agent temozolomide (TMZ). Epigenetic silencing of t...

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Udgivet i:Neuro Oncol
Main Authors: Struve, N., Brend, T., Ott, L., Petersen, C., Rothkamm, K., Short, S. C., Kriegs, M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782608/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.111
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