CBMT-16. EGFRvIII EXPRESSION CONFERS CHEMOSENSITIVITY BY INCREASING DNA MISMATCH REPAIR PROTEIN EXPRESSION AND REPLICATION STRESS

MGMT promoter methylation is the only accepted biomarker with prognostic role in GBM but its routine implementation is limited partly response to TMZ is heterogeneous, but also due to lack of effective alternative treatment options. Therefore, additional biomarkers are needed to enable better predic...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Struve, Nina, Binder, Zev A, Stead, Lucy F, Brend, Tim, Bagley, Stephen J, Faulkner, Claire, Ott, Leonie, Müller-Goebel, Justus, Weik, Anna-Sophie, Hoffer, Konstantin, Rieckmann, Thorsten, Christin Parplys, Ann, Burmester, Jasmin, Henze, Marvin, Morrissette, Jennifer J D, Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, Kurian, Kathreena M, Short, Susan C, Kriegs, Malte
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Cell Biology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847190/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.138
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