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Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies
Many neurodegenerative diseases, such as Huntington’s disease, are hallmarked by the formation of intracellular inclusion bodies (IBs) that are decorated with ubiquitin, proteasomes and chaperones. The apparent enrichment of ubiquitin and components involved in protein quality control at IBs suggest...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780509/ https://ncbi.nlm.nih.gov/pubmed/29362455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19538-0 |
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