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Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204

Live attenuated viruses are historically among the most effective viral vaccines. Development of a safe vaccine requires the virus to be less virulent, a phenotype that is historically arrived by empirical evaluation often leaving the mechanisms of attenuation unknown. The yellow fever virus 17D liv...

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Detalles Bibliográficos
Publicado en:NPJ Vaccines
Main Authors: Lam, L. K. Metthew, Watson, Alan M., Ryman, Kate D., Klimstra, William B.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780476/
https://ncbi.nlm.nih.gov/pubmed/29387474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-017-0039-z
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