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The 17D-204 Vaccine Strain-Induced Protection against Virulent Yellow Fever Virus Is Mediated by Humoral Immunity and CD4+ but not CD8+ T Cells

A gold standard of antiviral vaccination has been the safe and effective live-attenuated 17D-based yellow fever virus (YFV) vaccines. Among more than 500 million vaccinees, only a handful of cases have been reported in which vaccinees developed a virulent wild type YFV infection. This efficacy is pr...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Watson, Alan M., Lam, L. K. Metthew, Klimstra, William B., Ryman, Kate D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962991/
https://ncbi.nlm.nih.gov/pubmed/27463517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005786
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