Comparison of the Live Attenuated Yellow Fever Vaccine 17D-204 Strain to Its Virulent Parental Strain Asibi by Deep Sequencing

Background. The first comparison of a live RNA viral vaccine strain to its wild-type parental strain by deep sequencing is presented using as a model the yellow fever virus (YFV) live vaccine strain 17D-204 and its wild-type parental strain, Asibi. Methods. The YFV 17D-204 vaccine genome was compare...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beck, Andrew, Tesh, Robert B., Wood, Thomas G., Widen, Steven G., Ryman, Kate D., Barrett, Alan D. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883177/
https://ncbi.nlm.nih.gov/pubmed/24141982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit546
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